U.S., March 6 -- ClinicalTrials.gov registry received information related to the study (NCT06859671) titled 'A Randomized Study of a Short Duration Therapy for Candidemia' on Feb. 28.
Brief Summary: Scientific justification Candidemia is a major public health problem. In France, the 30-day mortality of candidemia varies from 30% to 50% depending on the need for intensive care and it has not decreased in 30 years.
The duration of treatment for candidemia was set at a minimum of 14 days after the last positive blood culture following the Rex trial (1) comparing the efficacy of fluconazole vs amphotericin B where the minimum duration of treatment was imposed. The risk of a too short treatment is the absence of control of the candidemia with ...