Clinical Trial: A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in Africa

U.S., Jan. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07379580) titled 'A Randomized Clinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in Africa' on Jan. 23.

Brief Summary: This is a randomized, double-blind, placebo-controlled study which aims to assess the safety, reactogenicity, and immunogenicity after one and two doses of BNT166a or placebo in healthy participants.

Study Start Date: Feb., 2026

Study Type: INTERVENTIONAL

Condition: Mpox (Monkeypox) Smallpox Orthopoxvirus Infection

Intervention: BIOLOGICAL: BNT166a

Intramuscular injection. Injections should be given in the deltoid muscle, using the same non-...