Clinical Trial: A Proof-of-concept Trial for OPC 131461 in Patients Hospitalized for Worsening Heart Failure

U.S., Jan. 29 -- ClinicalTrials.gov registry received information related to the study (NCT06795399) titled 'A Proof-of-concept Trial for OPC 131461 in Patients Hospitalized for Worsening Heart Failure' on Jan. 22.

Brief Summary: The primary objective of the study is to compare relative changes in blood N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels after 30 days of treatment in participants with worsening heart failure (WHF), who are treated with either OPC-131461 or placebo.

Study Start Date: Feb. 26

Study Type: INTERVENTIONAL

Condition: Heart Failure

Intervention: DRUG: OPC-131461

OPC-131461 will be administered as oral tablets.

DRUG: Placebo

OPC-131461 matched placebo will be administered as oral tablets.

Recrui...