U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT06917924) titled 'A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS' on March 12.
Brief Summary: Amyotrophic Lateral Sclerosis (ALS) is a severe and incurable neurodegenerative disease of motor neurons with a dramatic socio-economic impact on the national health system. ALS is a complex disorder with the majority of cases being sporadic and about 15% of cases showing familial history. It is characterized by high genetic heterogeneity, with more than 30 causative genes accounting for 60% of familial and 10% of sporadic cases. The clinical manifestations of ALS are variable with respect to age and site of onset, disease pro...