U.S., Feb. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07395882) titled 'A New Model to Induce Itch and Inflammation' on Feb. 02.
Brief Summary: This project aims to create a reliable, long-lasting itch model by synergistically combining thermal pre-conditioning with the application of histamine or cowhage.
Study Start Date: Feb. 15
Study Type: INTERVENTIONAL
Condition:
ITCH
Heat
Intervention:
OTHER: Cowhage (Mucuna Pruriens)
The spicules will be manually inserted. Approximately 30-35 spicules are gently rubbed into a 1 cm diameter skin area on the forearm/face
OTHER: Histamine
To deliver histamine, standard allergy skin prick test (SPT) lancets are applied
OTHER: Heat
45 degC x 5 min
Recruit...