Sydney, June 28 -- Researchers have created lab-grown heart tissues that closely mimic adult heart muscle, marking a significant advance in treating genetic heart diseases in children.
Scientists have successfully developed lab-grown miniature heart tissues, known as cardiac organoids, that closely replicate adult human heart muscle, announced yesterday by QIMR Berghofer Medical Research Institute in collaboration with the Melbourne-based Murdoch Children's Research Institute and the Royal Children's Hospital.
Created from human pluripotent stem cells, these organoids overcome a key limitation. Traditionally, stem-cell-derived heart cells remain immature. Researchers activated specific biological pathways to simulate exercise effects, m...