Hyderabad, May 7 -- In a groundbreaking discovery, scientists at the Centre for Cellular and Molecular Biology (CCMB) have revealed that the function of proteins is not solely determined by their fixed three-dimensional structures.
Instead, their ability to dynamically change shape plays a critical role in enabling them to interact with multiple molecular partners.
According to a study published in the Journal of the American Chemical Society, researchers found that two plant proteins with identical structures display different substrate specificities because one is significantly more flexible.
This flexibility allows the protein to bind with a broader range of RNA molecules by transiently rearranging itself to match the shape of its par...