Dhaka, March 3 -- Real Madrid slumped to a 2-1 defeat at Real Betis after their former player Isco converted a second-half penalty on Saturday, denying the visitors the chance to top La Liga.

The loss leaves Real Madrid level on 54 points with leaders Barcelona, who host mid-table Real Sociedad on Sunday.

Third-placed Atletico Madrid, who have 53, could go top later on Saturday when they host fourth-placed Athletic Bilbao.

"I'm dead, exhausted. In the end it's very hard to win games against Madrid, who have millions of resources, it's very difficult," Isco, named man of the match, told Movistar.

"I'm happy for the win against the best team out there today. Hopefully we can finish the year in the best possible way."

Madrid dominated the...