India, April 26 -- UroGen Pharma Ltd. (URGN) announced encouraging safety data from the Phase 1 dose-escalation study for UGN-301 (zalifrelimab) intravesical solution, an investigational drug in development for the treatment of recurrent non-muscle invasive bladder cancer (NMIBC).
The company noted that UGN-301 demonstrated tolerability across all dose levels, with no dose-limiting toxicities or adverse events resulting in treatment discontinuation. The formulation of UGN-301 in a reverse thermal gel enabled sustained bladder exposure.
Additionally, some patients treated with UGN-301 (zalifrelimab) intravesical solution exhibited clinical activity during the week 12 disease assessment. These findings were presented at the 2025 American Ur...