India, March 8 -- Regeneron Pharmaceuticals Inc. (REGN) and Sanofi presented positive results from the pivotal ADEPT Phase 2/3 trial evaluating the investigational use of Dupixent (dupilumab) in adults with moderate-to-severe bullous pemphigoid. The data were shared in a late-breaking oral presentation at the 2025 American Academy of Dermatology (AAD) Annual Meeting.
Adults on Dupixent experienced sustained disease remission five times more often at 36 weeks compared to those on a placebo. They also saw significant reductions in disease severity and itch. Additionally, Dupixent significantly reduced the use of oral corticosteroids and rescue medications compared to a placebo.
Bullous pemphigoid is a chronic, debilitating and relapsing ski...