India, April 21 -- Gilead Sciences, Inc. (GILD) Monday reported positive topline results from the Phase 3 ASCENT-04/KEYNOTE-D19 study evaluating Trodelvy in combination with Merck's Keytruda in patients with triple-negative breast cancer (mTNBC) whose tumors express PD-L1. The study met its primary goal.
In the study, Trodelvy in combination with Keytruda significantly improved progression-free survival (PFS) compared to Keytruda and chemotherapy in patients with mTNBC. Further, the safety profile of Trodelvy plus Keytruda was consistent with the known safety profile of each agent, and no new safety signals were identified with the combination.
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