New Delhi, Jan. 10 -- Russia said Friday it used its latest missile against Ukraine for a second time in the nearly 4-year-old war, a forceful signal to Kyiv and its Western allies as U.S.-led peace talks have entered a new and crucial stage.

The hypersonic Oreshnik intermediate range ballistic missile hit Ukraine's western Lviv region late Thursday night, although officials there did not mention any casualties. The area is near a military base in neighboring Poland, a NATO member, that serves as a key hub for ferrying Western military supplies to Kyiv.

Some Moscow commentators said the attack was a warning to European leaders against proposals to deploy their troops to Ukraine as part of a prospective peace deal. Russia has said it won...