Tokyo, July 29 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000058614) titled 'Analysis of the Impact of Alpha-2-glycoprotein 1, Zinc-binding on T Cell Immune Responses in Breast Cancer' on July 28.
Study Type:
Others,meta-analysis etc
Primary Sponsor:
Institute - Tokai University
Condition:
Condition - Breast Cancer
Classification by malignancy - Malignancy
Genomic information - NO
Objective:
Narrative objectives1 - Immune checkpoint inhibitors (ICIs) are effective in some breast cancers, but resistance is linked to hormone receptor signaling and immunosuppressive tumor microenvironments (TME). We previously showed that AR-dependent secretion of ZAG (alpha-2-glycoprotein 1) correlates with...