MUMBAI, India, June 20 -- Intellectual Property India has published a patent application (202517023417 A) filed by Affinia Therapeutics Inc., Waltham, U.S.A., on March 17, for 'recombinant aavs with improved tropism and specificity.'
Inventor(s) include Albright, Charles Francis; Olivieri, Kevin C; Cao, Xiaohong; and Tan, Jie.
The application for the patent was published on June 20, under issue no. 25/2025.
According to the abstract released by the Intellectual Property India: "The present disclosure provides a modified AAV capsid protein comprising a targeting peptide in variable region VIII (VR. VIII) and/or a peptide segment in variable region I (VR I). The modified AAV capsid protein can form an rAAV, which has a preferred tropism, s...