Intellectual Property India Publishes Patent Application for 'Novel Gene Therapy Construct For CLN2 Disease' Filed by The Children's Hospital Of Philadelphia

MUMBAI, India, Oct. 11 -- Intellectual Property India has published a patent application (202517071030 A) filed by The Children's Hospital Of Philadelphia, Philadelphia, on July 25, for 'novel gene therapy construct for cln2 disease.'

Inventor(s) include Davidson, Beverly; Ranum, Paul; Chen, Yonghong; Keiser, Megan S; and Tecedor, Luis.

The application for the patent was published on Oct. 10, under issue no. 41/2025.

According to the abstract released by the Intellectual Property India: "Provided herein are methods of expressing a tripeptidyl peptidase 1 (TPP1) in a neuron. Also provided herein is a modified adeno-associated virus (AAV) encoding a TPP1 under the control of a promoter operable in a neuron or ependyma cell, and not in dors...