Intellectual Property India Publishes Patent Application for 'Methods Of Making Tolebrutinib' Filed by Principia Biopharma Inc.

MUMBAI, India, Feb. 28 -- Intellectual Property India has published a patent application (202517002928 A) filed by Principia Biopharma Inc., Bridgewater, U.S.A., on Jan. 13, for 'methods of making tolebrutinib.'

Inventor(s) include Sodo, Alfred; Rodier, Fabien; Janssens, Laurence; Cabos, Claude; Borie, Cyril; Bailly, Frederic; Benelli, Christophe; Bosch, Michael; Charaudeau, Alexis; Pacquet, Francois; Salle, Laurent; and Vigne, Sylvie.

The application for the patent was published on Feb. 28, under issue no. 09/2025.

According to the abstract released by the Intellectual Property India: "Disclosed herein are improved synthetic routes for making (R)-1-(1-acryloylpiperidin-3-yl)-4-amino-3-(4-phenoxyphenyl)-1 H-imidazo[4,5-c ]pyridin-2(3H)-o...