India, Jan. 28 -- Researchers have developed a targeted nano formulation that can help sustained release of a hormone called 17 -Estradiol which is crucial for managing Parkinson's Disease (PD).

Many neurodegenerative and psychiatric malignancies like Parkinson' disease (PD) originate from an imbalance of 17 -Estradiol (E2) in the human brain. However, the peripheral side effects of the usage of E2 for PD therapy and less understanding of the molecular mechanism hinder establishing its neurotherapeutic potential.

Scientists from Institute of Nano Science and Technology (INST) Mohali, an autonomous institute of Department of Science and Technology, used Dopamine Receptor D3 (DRD3) conjugated to 17 -Estradiol-loaded chitosan nanoparticle...