India, Dec. 27 -- Obesity is a global epidemic and a major cause of morbidity and mortality because it increases the risk for comorbidities, including heart disease and fatty liver disease (MASLD). Rates of these disorders have risen as the world increasingly adopts energy-dense diets and sedentary lifestyles.

Nitric oxide is a gas molecule with pleiotropic actions in the body. These effects of nitric oxide are carried out through its binding to proteins. Too much or too little nitric oxide binding (to key proteins) causes disease, reads the Harrington Discovery Institute at University Hospitals website.

In a new study, published December 23rd in the AAAS journal, Science Signaling, a research team from University Hospitals and Case Wes...