India, July 5 -- Shefali Jariwala's untimely death at 42 has come as a shock and raised concerns over the use of cosmetic procedures like anti-ageing injections. We speak to experts if these injections actually work and what are the risks involved. Dr Jyoti Kusnur, consultant and interventional cardiologist at Manipal Hospital, Goa says, "There is no proven research that substantiates the existence of any 'anti-ageing therapies'; however, several beauty consultants claim cosmetic benefits by administering different compounds." She notes that anti-ageing injections include a range of substances, such as Botox, long used for wrinkle treatment. In Shefali's case, speculation points to the use of glutathione injections. "Any therapy that is not medically supervised or indicated is best avoided. In the absence of any verified data relating to the formulation and production of these substances, as well as their therapeutic effects on the human body, it would be very difficult to ascertain the damage they cause. In this instance, certain additives might have caused allergic reactions or anaphylaxis, causing blood pressure to fall to dangerous levels, thereby precipitating a cardiac arrest," Dr Kusnur explains. Dr Karthik Shrinivas Tallam, senior consultant of plastic and reconstructive surgery at Manipal Hospital Varthur, cites a few examples of these treatments, saying, "Anti-ageing treatments can be IV injections, skin, or subcutaneous injections. Anti-ageing injections given by an IV are glutathione injections. These injections act as an antioxidant. Oxidation of cells leads to ageing; hence, antioxidants will slow the ageing of the cells." The plastic surgeon asserts, "Treatments done by certified physicians will have the least risks, as they will be assessed prior to the procedure. Always get the procedures done at a certified hospital which has other specialities to take care of in case of an untoward event or complication." With inputs by Kaavya Sharma...