Goa, July 29 -- A lone gunman opened fire at a Midtown Manhattan high-rise on Monday evening, injuring an NYPD officer and at least two civilians before taking his own life, police said.

The shooting occurred around 6:30 p.m. at 345 Park Avenue, home to several prominent offices including Blackstone and the NFL's headquarters. The suspect, who reportedly entered the building carrying a long gun and wearing dark sunglasses and a jacket, made his way to the 33rd floor, where he died by suicide, according to law enforcement sources.

New York Police Commissioner Jessica Tisch confirmed that the situation had been brought under control and that "the lone shooter has been neutralized." The building was placed under lockdown, with occupants or...