U.S., Feb. 8 -- ClinicalTrials.gov registry received information related to the study (NCT06248931) titled 'Valproate Versus Topiramate in Migraine' on Jan. 31.
Brief Summary: Investigators aim to compare the effect of valproate versus topiramate in migraine by assessing the absolute reduction in MMD in each group, the percentage of patients who achieved >= 50% reduction in the monthly headache days frequency compared to the baseline frequency.
Study Type: Interventional
Condition: Migraine Disorders
Intervention: * Drug: Valproic acid
The arm will include 300 migraine patients diagnosed according to ICHD3-beta criteria. All patients will receive valproate 500-1000 mg daily and Acetaminophen 500-1000 mg only in acute migraine attacks f...