U.S., Feb. 8 -- ClinicalTrials.gov registry received information related to the study (NCT06249048) titled 'Phase 1/2 Study of IT STX-001 in Patients With Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab' on Feb. 2.
Brief Summary: Phase 1/2, Open-label, Multi-center, First-in-human Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of STX-001 Delivered by Intratumoral Injection in Patients with Advanced Solid Tumors as a Monotherapy or in Combination with Pembrolizumab
Study Type: Interventional
Condition: Advanced Solid Tumor
Intervention: * Biological: STX-001
STX-001 encapsulates a self-replicating RNA encoded for IL-12, contained within an LNP for intratumoral inje...