U.S., May 16 -- ClinicalTrials.gov registry received information related to the study (NCT06416566) titled 'Low-Dose Enoxaparin in Psoriasis' on May 10.
Brief Summary: Rationale:
* Psoriasis is a chronic immune-mediated inflammatory skin disorder where T cells play a fundamental role in its pathogenesis.
* Low molecular weight heparin has been reported to exert immunomodulatory effect at small doses through inhibition of T cells heparinase enzyme.
* Low molecular weight heparin may have promising results for treatment of psoriasis.
Research question:
* Can low molecular weight heparin be used safely for treatment of psoriasis with good outcome?
* Is enoxaparin inhibitory effect on T cell heparinase enzyme responsible for its benefici...