U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT04840095) titled 'Dynamic Connectivity Under Metabolic Constraints' on April 7.
Brief Summary: In this study, we investigate the impact of insulin resistance on the acceleration of brain aging, and test whether increased neuron insulin resistance can be counteracted by utilization of alternate metabolic pathways (e.g., ketones rather than glucose). This study has three Arms, which together provide synergistic data. For all three Arms, subjects are tested in a within-subjects design that consists of 2-3 testing sessions, 1-14 days apart, and counter-balanced for order. During each session we measure the impact of fuel (glucose in one session, ketones...