Clinical Trial: Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping

U.S., June 17 -- ClinicalTrials.gov registry received information related to the study (NCT04928976) titled 'Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping' on May 20.

Brief Summary: The primary objective of the study is to evaluate whether a set of algorithms analysing acoustic and linguistic patterns of speech can detect amyloid-specific cognitive impairment in early stage Alzheimer's disease, as measured by the AUC of the receiver operating characteristic (ROC) curve of the binary classifier distinguishing between amyloid positive (Arms 1 and 3) and amyloid negative (Arms 2 and 4) Arms. Secondary objectives include (1) evaluating whether similar algorithms can detect amyloid-specific cognitive impairmen...