Clinical Trial: A Single Ascending Dose Study to Assess the Safety and Pharmacokinetics of Intra-articular AVD275 Injection in Patients With Osteoarthritis of the Knee

U.S., Jan. 14 -- ClinicalTrials.gov registry received information related to the study (NCT07338266) titled 'A Single Ascending Dose Study to Assess the Safety and Pharmacokinetics of Intra-articular AVD275 Injection in Patients With Osteoarthritis of the Knee' on Jan. 03.

Brief Summary: This study aims to understand the safety, drug concentration and distribution of an intra-articular injectable formulation of celecoxib, AVD275, in patients with knee osteoarthritis. One single injection at three different doses of the drug will be studied in a sequential order, and each participant will be monitored for 24 weeks over ten clinical visits.

Study Start Date: Jan., 2026

Study Type: INTERVENTIONAL

Condition: Osteoarthritis of the Knee

Int...