Singapore, April 13 -- The Institute of Mental Health (IMH), in collaboration with the Yong Loo Lin School of Medicine at the National University of Singapore (NUS Medicine), has embarked on two clinical pilots to study the efficacy of personalised Transcranial Magnetic Stimulation (TMS) in treating persons with treatment-resistant depression (TRD).

The trials, named APIC-TMS (Asia Pacific Individual Connectomics - Transcranial Magnetic Stimulation) and SPARK-D (Singapore's Precision Approach for Relief from Depression), are catalysed by Temasek Foundation (TF) and the National Medical Research Council (NMRC) respectively, with a grant of S$1 million each.

Both clinical trials will run concurrently from March 2024 to 2026. Both trials w...