Singapore, Nov. 5 -- Samsung Biologics has announced the signing of a long-term agreement with Ichnos Sciences for manufacturing drug substance for ISB 830, an anti-OX40 monoclonal antibody in development as a potential treatment for moderate-to-severe atopic dermatitis.

Based on an entirely new mechanism of action, ISB 830 has the potential to treat a range of autoimmune diseases beyond atopic dermatitis. Enrollment in a large randomized placebo-controlled Phase 2b study in atopic dermatitis was recently completed and results are expected in the first half of 2020.

The prevalence of atopic dermatitis in the seven major markets (US, France, Germany, Italy, Spain, the UK, and Japan) currently exceeds 80 million patients and the market is...