United Kingdom, Aug. 2 -- Seth Rogen considers on-screen chemistry to be a "mysterious thing".

The 43-year-old actor has developed a very successful working partnership with Rose Byrne over the years, but Seth struggles to explain why some actors form such productive partnerships.

Seth - who stars alongside Rose in Platonic, the TV comedy series - told The Hollywood Reporter: "In film chemistry is a mysterious thing; you never know who you're going to have good chemistry with.

"There's people who are great friends in real life that have terrible chemistry on screen. I've had great chemistry with people I don't particularly like that much, and so I'm very lucky in this situation where I have chemistry with someone who I actually like. S...