India, April 30 -- Mediawire

New Delhi [India], April 30: Pulmonary fibrosis (PF) is a progressive interstitial lung disease (ILD) characterized by excessive fibrotic tissue deposition in the pulmonary parenchyma. The term "pulmonary" refers to the lungs, while "fibrosis" denotes pathological scarring. The disease disrupts normal alveolar architecture, leading to impaired gas exchange, reduced lung compliance, and progressive respiratory insufficiency.

PF encompasses over 200 ILDs, with idiopathic pulmonary fibrosis (IPF) being the most common and severe form. Histopathologically, PF features chronic inflammation, fibroblast proliferation, and excessive extracellular matrix deposition, predominantly collagen. Unlike inflammatory ILDs, I...