Washington, Sept. 18 -- : A new discovery from researchers at The University of Texas MD Anderson Cancer Center has clarified the long-established connection between inflammation and pancreatic cancer development.
The findings of the study were published in the journal 'Science'.
According to the study, pancreatic cells display an adaptive response to repeated inflammatory episodes that initially protects against tissue damage but can promote tumour formation in the presence of mutant KRAS.
The authors demonstrated that mutant KRAS -- which is found in roughly 95 per cent of all pancreatic cancers -- supports this adaptive response, leading to selective pressure to maintain the cancer-causing mutation.
"We discovered that a single trans...