Washington D.C., April 10 -- : A recent study has pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease (IBD). The genetic pathway associated with this variation is involved in other immune disorders that could serve as an important therapeutic target.
The study conducted by researchers at Children's Hospital of Philadelphia (CHOP) was published in the Journal of Crohn's and Colitis.
The two main forms of IBD, Crohn's disease and ulcerative colitis have an important genetic component. More than 240 genetic regions have been identified that associate with IBD, more than any other pathological condition that has been studied. However, as each genetic region has multiple markers, it's important ...