Indiana, April 8 -- : Worldwide, 1 in 4 people are suffering from depression. While current diagnosis and treatment approaches are largely trial and error, a breakthrough study by Indiana University School of Medicine sheds new light on the biological basis of mood disorders and offers a promising blood test aimed at a precision medicine approach to treatment.

Led by Alexander B. Niculescu, MD, PhD, Professor of Psychiatry at IU School of Medicine, the study was published today in the high impact journal Molecular Psychiatry. The work builds on previous research conducted by Niculescu and his colleagues into blood biomarkers that track suicidality as well as pain, post-traumatic stress disorder and Alzheimer's disease.

"We have pioneered ...