Washington D.C., June 30 -- : Neurons that regularly remodel are more prone to the dysfunctions linked to Alzheimer's disease, according to a new study.
"Identifying the molecular characteristics of neurons that are especially vulnerable to neurodegeneration is important both for the basic understanding of Alzheimer's and for the future development of better diagnostic and treatment options," said study co-author Olga Troyanskaya, deputy director for genomics at the Flatiron Institute's Center for Computational Biology in New York City and a professor at Princeton University.
Using a machine learning framework that integrated neuron type-specific mouse experiments with human studies, the researchers compared two types of neurons susceptib...