Washington, April 10 -- Comedian and actor Eric Andre opened up about one of his biggest professional regrets. It was turning down Kieran Culkin's Oscar-winning role in the comedy-drama film A Real Pain, directed by Jesse Eisenberg.

"I was working on something else when I read the script. I read the script. It was like 120 pages about two Jews babbling about the Holocaust, and that seemed a bit depressing to me upon first read. And I was like, 'You know what? I'm a comedian; I want to stay in my lane as a comedian,'" he said during his appearance on Jimmy Kimmel Live!, reported People.

Andre shared that he was not sure if the movie was right for "my brand." Recalling it, he shared, it was "the biggest mistake of my entire career."

Kimm...