US Patent Issued to ZYMERON on Aug. 12 for "Injectable formulations of PARP inhibitors and uses thereof" (North Carolina Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,633, issued on Aug. 12, was assigned to ZYMERON Corp. (Research Triangle Park, N.C.).

"Injectable formulations of PARP inhibitors and uses thereof" was invented by Xu Li (Research Triangle Park, N.C.), Zhiguo Zhou (Research Triangle Park, N.C.), Krishan Kumar (Research Triangle Park, N.C.) and Chunyan Cao (Research Triangle Park, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are injectable or infusible formulations of PARP inhibitors. In one aspect, the formulation comprises a PARP inhibitor and a cyclodextrin. The injectable or infusible PARP inhibitor-cyclodextrin formulation improves drug solubility, bioavailability, and th...