US Patent Issued to YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, SpliSense on July 8 for "Restoration of the CFTR function by splicing modulation" (Israeli Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,803, issued on July 8, was assigned to YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (Jerusalem) and SpliSense Ltd. (Jerusalem).

"Restoration of the CFTR function by splicing modulation" was invented by Bat Sheva Kerem (Mevaseret Zion, Israel), Efrat Ozeri-Galai (Jerusalem), Yifat Oren (Jerusalem) and Ofra Barchad-Avitzur (Jerusalem).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides oligonucleotides capable of binding to and modulating the splicing of the pre-mRNA of the CFTR gene, including compositions comprising the oligonucleotides, and uses thereof, such as for suppressing the inclusion...