ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,747, issued on March 18, was assigned to Wisconsin Alumni Research Foundation (Madison, Wis.).
"Unbiased DNA methylation markers define an extensive field defect in histologically normal prostate tissues associated with prostate cancer: new biomarkers for men with prostate cancer" was invented by David Frazier Jarrard (Madison, Wis.) and Bing Yang (Madison, Wis.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of detecting the presence of a prostate cancer field defect in a human subject comprising the step of (a) obtaining genomic DNA from the human subject and (b) quantitating methylation in at least one target region selected from the gro...