ALEXANDRIA, Va., March 5 -- United States Patent no. 12,241,072, issued on March 4, was assigned to Whitehead Institute for Biomedical Research (Cambridge, Mass.).
"Biosynthetic approach for heterologous production and diversification of bioactive lyciumin cyclic peptides" was invented by Roland D. Kersten (Arlington, Mass.) and Jing-Ke Weng (Belmont, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Lyciumin cyclic peptides and methods of producing lyciumin cyclic peptides are described. A host cell can include a transgene encoding a lyciumin precursor peptide, or a biologically-active fragment thereof. The lyciumin precursor peptide, or biologically-active fragment thereof, can include one or more core ...