US Patent Issued to Washington University on July 8 for "Gene editing of CAR-T cells for the treatment of T cell malignancies with chimeric antigen receptors" (Missouri Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,349, issued on July 8, was assigned to Washington University (St. Louis).

"Gene editing of CAR-T cells for the treatment of T cell malignancies with chimeric antigen receptors" was invented by John F. DiPersio (St. Louis) and Matthew Cooper (St. Louis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides the use of fratricide-resistant chimeric antigen receptor T (CAR-T) cells targeting antigens expressed by T cell malignancies."

The patent was filed on Aug. 3, 2017, under Application No. 16/322,803.

*For further information, including images, charts and tables, please visit: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=...