US Patent Issued to Washington University on July 22 for "Use of pirfenidone and derivatives for modulation of B lymphocyte activity and organ protection from acute tissue damage" (Missouri Inventors)

ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,651, issued on July 22, was assigned to Washington University (St. Louis).

"Use of pirfenidone and derivatives for modulation of B lymphocyte activity and organ protection from acute tissue damage" was invented by Luigi Adamo (St. Louis), Douglas L. Mann (St. Louis) and Roland Dolle (St. Louis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compositions and methods of modulating B lymphocyte activity, and organ protection after acute injury. In particular, PEG-Pirfenidone has increased half-life, improved bioavailability and is equipotent in modulating B cell activity and is particularly useful as protective agents f...