ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,508,306, issued on Dec. 30, was assigned to Washington University (St. Louis).

"Compositions and methods of use thereof for treatment of metabolic diseases and related disorders" was invented by Brian J. Debosch (St. Louis), Cassandra Higgins (St. Louis), Yiming Zhang (St. Louis) and Allyson Mayer (St. Louis).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compositions and methods of using the same for the treatment of various metabolic diseases and related disorders (e.g. diabetes mellitus, NAFLD, obesity, metabolic syndrome). The compositions and methods of the disclosure relate to the administration of an arginine-degr...