ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,255, issued on June 24, was assigned to Viva Star Biosciences (Suzhou) Co. Ltd. (Jiangsu, China).

"Bicyclic substituted sulfonylurea compounds as inhibitors of interleukin-1 activity" was invented by Ping Chen (Shanghai), Hongjian Zhang (Plainsboro, N.J.), Fei Jiang (Shanghai) and Peihua Sun (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "This application relates to novel bicyclic substituted sulfonylurea compounds and analogues, their manufacture, pharmaceutical compositions comprising them, and their use as medicaments for treating a disease associated with modulation of cytokines such as IL-1Beta and IL-18, modulation of NLRP3, or inhibi...