US Patent Issued to Vertex Pharmaceuticals on Dec. 23 for "Pyrano[4,3-bindole derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD)" (Massachusetts, California, New Hampshire, North Carolina Inventors)

ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,502,376, issued on Dec. 23, was assigned to Vertex Pharmaceuticals Inc. (Boston).

"Pyrano[4,3-bindole derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD)" was invented by Michael Philip Clark (Concord, Mass.), Simon Giroux (Cambridge, Mass.), Philip Noel Collier (Hingham, Mass.), Qing Tang (Boxborough, Mass.), Nathan D. Waal (Somerville, Mass.), Sarathy Kesavan (Quincy, Mass.), Peter Jones (Sharon, Mass.), Michael Aaron Brodney (Newton, Mass.), Wenxin Gu (Concord, Mass.), Diane Marie Boucher (Beverly, Mass.), Lev T.D. Fanning (San Marcos, Calif.), Amy B. Hall (Wellesley Hills, Mass.), Dennis James Hurley (San Marcos, Calif.), Mac Arthur Joh...