US Patent Issued to Vanderbilt University on June 17 for "Substituted pyrimido[1,2-bpyridazines as positive allosteric modulators of the muscarinic acetylcholine receptor M4" (American, Danish Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,055, issued on June 17, was assigned to Vanderbilt University (Nashville, Tenn.).

"Substituted pyrimido[1,2-bpyridazines as positive allosteric modulators of the muscarinic acetylcholine receptor M4" was invented by Craig W. Lindsley (Brentwood, Tenn.), P. Jeffrey Conn (Nashville, Tenn.), Darren W. Engers (Brentwood, Tenn.), Alison R. Gregro (Mount Juliet, Tenn.), Kayla J. Temple (Spring Hill, Tenn.), Madeline F. Long (Nashville, Tenn.), Anna E. Ringuette (Nashville, Tenn.), Logan A. Baker (Thompson's Station, Tenn.) and Thomas Jensen (Valby, Denmark).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are analogues of 6-(4-((2,3-dihydrob...