US Patent Issued to University of Vermont and State Agricultural College on Nov. 4 for "Cell primed with CTGF-D4 and insulin or IGF-1 and use in methods for cardiac tissue repair" (Vermont Inventor)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,184, issued on Nov. 4, was assigned to University of Vermont and State Agricultural College (Burlington, Vt.).

"Cell primed with CTGF-D4 and insulin or IGF-1 and use in methods for cardiac tissue repair" was invented by Jeffrey Spees (Burlington, Vt.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention features compositions featuring (a) one or more of connective tissue growth factor (CTGF) and human C-terminal CTGF peptide; and (b) one or more of insulin and IGF-1; and methods of using such compositions to reduce cardiac tissue damage associated with an ischemic event or to enhance engraftment of a cell in a cardiac tissue."

The patent was ...