ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,428, issued on Sept. 9, was assigned to University of Utah Research Foundation (Salt Lake City).

"RNA-guided transcriptional regulation and methods of using the same for the treatment of back pain" was invented by Robert Daniel Bowles (Salt Lake City), Niloofar Farhang (Salt Lake City), David Ede (Salt Lake City) and Jacob Weston (Salt Lake City).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compositions and methods for treatment and prevention of low back pain. The compositions include vectors comprising nucleotide sequences encoding one or more CRISPR-Cas system guide RNAs and a RNA-directed nuclease. The methods include modu...