US Patent Issued to UNIVERSITY OF SOUTH FLORIDA, H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE on Sept. 16 for "B-catenin/B-cell Lymphoma 9 protein-protein interaction inhibiting peptidomimetics" (Florida Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,832, issued on Sept. 16, was assigned to UNIVERSITY OF SOUTH FLORIDA (Tampa, Fla.) and H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC. (Tampa, Fla.).

"B-catenin/B-cell Lymphoma 9 protein-protein interaction inhibiting peptidomimetics" was invented by Jianfeng Cai (Tampa, Fla.), Peng Sang (Tampa, Fla.), Yan Shi (Tampa, Fla.), Haitao Ji (Tampa, Fla.) and Min Zhang (Tampa, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is a series of helical sulfono-Gamma-AApeptides that mimic the binding mode of the Alpha-helical HD2 domain of B-Cell Lymphoma 9 (BCL9). As disclosed herein, sulfono-Gamma-AApeptides can structurally and f...