US Patent Issued to University of South Carolina on Dec. 30 for "Acetylation of Miro1" (South Carolina Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,508,303, issued on Dec. 30, was assigned to University of South Carolina (Columbia, S.C.).

"Acetylation of Miro1" was invented by Jeffery L. Twiss (Columbia, S.C.) and Amar N. Kar (Lexington, S.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Deacetylation of rat Miro1 on Lysine 105 attenuates axon growth on nonpermissive substrates by making mitochondria more sensitive to Ca levels, depolarizing mitochondrial membranes and blocking mitochondrial transport; the current disclosure provides an antibody that specifically recognizes the lysine 105 acetylated and not the deacetylated Miro1 protein."

The patent was filed on March 1, 2021, under Application ...