ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,444, issued on Oct. 14, was assigned to University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh).

"Matrix bound vesicles (MBVS) containing IL-33 and their use" was invented by Stephen Francis Badylak (West Lafayette, Ind.), George S. Hussey (Cranberry Township, Pa.), Heth Turnquist (Pittsburgh), Jenna Lynn Dziki (Pittsburgh), Quan Liu (Shenzhen, China) and Zhongqiang Zhang (Changsha, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods are disclosed for treating a subject with a disorder, such as, but not limited to, a) fibrosis of an organ or tissue; b) solid organ transplant rejection; or c) a cardiac disease th...